Progressive Nonfluent Aphasias
《英文msh詞典》Progressive Nonfluent Aphasias
[入口詞] Progressive Nonfluent Aphasias
[主題詞] Aphasia,Primary Progressive
[英文釋義] A progressive form of dementia characterized by the global loss of language abilities and initial preservation of other cognitive functions. Fluent and nonfluent subtypes have been described. Eventually a pattern of global cognitive dysfunction,similar to ALZHEIMER DISEASE,emerges. Pathologically,there are no Alzheimer or PICK DISEASE like changes,however,spongiform changes of cortical layers II and III are present in the TEMPORAL LOBE and FRONTAL LOBE. (From Brain 1998 Jan;121(Pt 1):115-26)